Locate a Rep:

CLARITY, SeeDB, SCALEVIEW

Tissue clearing with the SCALEVIEW-A2, CLARITY and SeeDB clearing techniques has opened up new possibilities for deep imaging. When coupled with clearing, Olympus Multi-Immersion objectives now allow researchers to reconstruct vast tissue areas at high resolution with the FV1200, FV1200MPE, and FVMPE-RS systems.
Product Image

GO DEEPER WITH NEW MULTI-IMMERSION OBJECTIVES FOR CLARITY, SEEDB AND SCALEVIEW CLEARING TECHNIQUES

NEW! MULTI-IMMERSION 10X

Extraordinary 8mm WD with massive refractive index correction from 1.33 to 1.52, for immersion from water to oil. The large field of view and widefield collection design ensures capture of brilliant images for multiple applications.

NEW! CLARITY, SEEDB OPTIMIZED 25X

Take advantage of high resolution imaging up to 8mm with this lens tailored to the new CLARITY and SeeDB clearing techniques.



Image courtesy of Dr. Raju Tomer, Deisseroth Lab, Stanford University. Image acquired with FV1200 confocal system using 515nm laser and CLARITY matched 25x lens. Sample: CLARITY processed Thy1-eYFP expressing mouse brain.
(Click Image to Enlarge)

REACH REVOLUTIONARY NEW IMAGING DEPTHS WITH THE WIDEST RANGE OF LONG WORKING DISTANCE MULTI-IMMERSION OPTICS FOR CLEARED OR LIVE TISSUE

Olympus now adds extraordinary new multi-immersion optics with refractive index matching for CLARITY, and SeeDB. Adding to Olympus SCALEVIEW objectives, which have received multiple honors, these long working distance objectives help facilitate breakthrough research on the functioning of the brain and other vital organs. Until recently, brain science researchers using light microscopes had to slice thin sections of tissue. Every cut damaged and potentially deformed the samples, and the tissue itself was so opaque that it scattered most light. But with the new objectives, researchers can see up to 8 mm deep without slicing. This allows them to see the tangled, complex interconnectedness of the brain much more clearly. Having a better understanding the brain’s functioning could ultimately help sufferers with Parkinson’s, autism, Alzheimer’s, traumatic injuries and more.

The new objectives work so well because they were specifically designed and engineered for use with the Scale reagent from the lab of Dr. Atsushi Miyawaki, the CLARITY method from the Deisseroth lab (Stanford University) and SeeDB (RIKEN).). Using these techniques, tissue is made nearly transparent; scientists can now see the interconnectedness in brain and other tissues as never before.

Gold Edison Award

Olympus SCALEVIEW microscope optics was awarded the prestigious Gold Edison Award in the Science/Medical category. The internationally known Edison Awards honor the best in innovation and excellence in the development of new products and services.

Click here to read more.

R&D 100 Award

Recognized as among the 100 most technologically significant products introduced last year, the Olympus SCALEVIEW 4 mm and 8 mm microscope objectives have earned the prestigious 2012 R&D 100 Award.

Click here to read more.

Microscopy Today Top 10 Innovation Award

The Olympus 4 mm and 8 mm SCALEVIEW microscope objectives were judged among the year’s ten best microscopy innovations in the 2012 Microscopy Today Innovation Award competition.

Click here to read more.

SCALEVIEW Immersion 25X Objective for Multiphoton

Specially designed to deliver optimum performance with SCALEVIEW immersion, this dedicated multiphoton objective with an ultra-long working distance enables high-precision imaging of tansparent-rendered biological specimens to a depth of 4 mm.

24 tiled areas composed of nearly
9000 images stitched together using
FluoView stage control and stitching
software, 4mm SCALEVIEW
objective.
Single Z-stack
acquisition with 4mm
SCALEVIEW
objective.
Single Z-stack
acquisition with
8mm SCALEVIEW
objective.
Image data courtesy of:
Hiroshi Hama, Hiroshi Kurokawa, Atsushi Miyawaki
Laboratory for Cell Function Dynamics, RIKEN Brain Science Institute
Reference material:
Hiroshi Hama, Hiroshi Kurokawa, Hiroyuki Kawano, Ryoko Ando,
Tomomi Shimogori, Hisayori Noda, Kiyoko Fukami,
Asako Sakaue-Sawano & Atsushi Miyawaki
"Scale: a chemical approach for fluorescence imaging and reconstruction of
transparent mouse brain," Nature Neuroscience, advance online publication, 30 August 2011 (doi:10.1038/nn.2928)

Imaris is a registered trademark of Bitplane AG.
  • BX3 fits meDP80
  • special promoLV200
  • VS120 Slide Systemfvmpe_rs
  • Specialty Objectives Imaris by Bitplane
  • CX22cellsens Digital Imaging Software